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The aromatic amino acids tyrosine and phenylalanine were significantly higher and trending higher, respectively, in the KD group
However, where priority determination is for an identical medicine and indication (or a subset of indication) as the orphan designation, applications for determination/designation can be submitted simultaneously with joint justification for certain eligibility criteria [23, 24]
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Restoration of lysosomal activity has been shown to enhance oocyte quality and embryonic developmental potential [322]
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Liraglutide has resulted in greater HbA 1c and weight reductions in comparison with the other GLP-1 RAs in three clinical trials (Buse et al, 2009
