T2DM is a metabolic disease caused by acquired endocrine disorders
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Gastric inhibitory polypeptide as an endogenous factor promoting new bone formation after food ingestion
After entering the cochlea, cisplatin is taken up into cells by diffusive and passive transport, copper transporter protein 1 (Ctr1) and organic cation transporter protein 2 (OCT2), endocytosis, and toxicity through DNA adduct formation, oxidative stress, mitochondrial dysfunction, inflammatory response, and ferroptosis ( 2.1 Cisplatin-induced DNA damage and apoptosis Once cisplatin enters the cell it can be hydrolyzed to form toxic aqua-cisplatin complexes and form intra-and interstrand crosslinks with DNA (Mukherjea et al., 2011)
B12 vitamins alongside B6 and folate can alleviate any risk of breast cancer
Garrison KL, Sahin S, Benet LZ