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PYY(3-36) itself has been studied as a monotherapy for weight loss when delivered nasally in human volunteers, but the efficacy in terms of weight loss was limited by dose-dependent adverse events in the form of nausea and vomiting [44], possibly because this preparation and method of delivery led to a rapid release of PYY(3-36) to supraphysiological levels

2013 Dec;42:132-55

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BPC-157 is not a painkiller that masks symptoms

IBS tissue samples show a lower GR activity than normal colon tissue

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