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2 Otoprotection in Zebrafish Lateral Line Hair Cells Uribe et al., Frontiers in Cellular Neuroscience (2015) This paper from the Coffin laboratory (with WSU co-authors) tested whether Dihexa could protect zebrafish lateral line hair cells (homologous to mammalian inner ear hair cells) from aminoglycoside-induced ototoxicity
TB-500 interacts with G-actin through the conserved LKKTET motif, influencing actin polymerization dynamics, cytoskeletal organization, and actin-associated signaling pathways
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The timeline for sphincter improvement in animal studies varies based on administration route and severity of dysfunction
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