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This coordination sphere provides exceptional stability, with a formation constant (log K) of approximately 16.2, significantly higher than most biological copper chelators

Access this article Similar content being viewed by others Abbreviations IBD: Inflammatory bowel disease UC: Ulcerative colitis CD: Crohn's disease NOD2: Nucleotide-binding oligomerisation domain 2 CARD9: Caspase recruitment domain Family 9 ATG16L: Autophagy-related 16 like IRGM: Immunity relayed GTPase M FUT2: Fucosyl transferase 2 HMOs: Human milk oligosaccharides TNF: Tumour necrosis factor CRH: Corticotropin-releasing hormone ROS: Reactive oxygen species TJ: Tight junctions STAT: Signal Transducer and Activator of Transcription PAMPs: Pathogen-associated molecular patterns DAMPs: Danger-associated molecular patterns CSs: Oral corticosteroids TPs: Thiopurines MTX: Methotrexate JAK: Janus Kinase inhibitors CAMs: Cell adhesion molecules MAdCAM: Mucosal addressin cell adhesion molecule IL: Interleukin References Abiodun O, Ogunleye F, Ben-upaka E (2020) Protective effect of trichilia monadelpha (tm) thonn j.j