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Physiol Rev 87(4):14091439 Holst JJ, Vilsbll T, Deacon CF (2009) The incretin system and its role in type 2 diabetes mellitus
For patients on weight management formulations (Wegovy, Saxenda, Zepbound), providers should follow FDA label guidance to monitor for suicidal thoughts or behaviors and discontinue medication if these occur
We usually see about 20% to 35% reduced intake from fatty foods, better eating control, and fewer cravings for energy-dense options, leading to 24% total daily energy reduction, says Jane
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these signaling molecules can enter the circulation and act directly on the brain, or they can act indirectly via paracrine action on local vagal and spinal afferent neurons that innervate the gut
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