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Three studies comprising 41,984 exposed pregnancies and 136,485 comparator pregnancies found no statistically significant association with cardiac congenital malformations (OR 0.92

This can result from reduced caloric intake (eating significantly less without adjusting activity levels), mild dehydration (reduced food intake often means reduced water intake from food), or blood sugar adjustments as the medication modifies glucose metabolism

[23] In contrast, patches only appeared in 2025

Verhoef et al, 1994), and peripheral vascular (Mansoor et al, 1995) diseases, as well as venous thrombosis (den Heijer et al, 1996) (also reviewed in Refsum et al, 1998)

GLP-1 helps regulate blood sugar levels and promotes feelings of fullness after eating

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