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GIP promotes clearance of circulating triglycerides and free fatty acids and enhances adipose tissue triglyceride absorption, serving as a crucial hormonal regulator of postprandial triglyceride response in humans (173175)

These can include headache, mild gastrointestinal discomfort such as nausea, difficulty sleeping, increased bruising tendency, and changes in mood

Similarly, metabolites potentially derived from gut microbiota were reported to be associated with renal and cerebrovascular endothelial, podocyte, and proximal tubule damage in early diabetic kidney disease in diabetes Mellitus patients (Balint et al., 2023b)

The dosage may be adjusted based on your response to the treatment and any side effects you may experience

it works better when taken along with a good diet and regular physical activity

The separate TRANSCEND-T2D Phase 3 program covers type 2 diabetes (TRANSCEND-T2D-1 reported topline results March 19, 2026)