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doi:10.1097/MCP.0000000000000628 Aurora RN, Chowdhuri S, Ramar K, et al

Heymsfield (2024)

Even at this lower starting dose, if treatment were discontinued, it would still take approximately five to six weeks for the semaglutide to be substantially cleared from your body

But if that rolling average has been flat, truly flat, for three weeks or more

The goal is to build a sustainable habit and foundation first, gradually progressing towards more structured intensity targets as fitness, confidence, and tolerance to medication improve