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At 12 months, discontinuation rates reach 60%, according to real-world analysis by Helmstadter et al., published in the International Journal of Diabetes and Clinical Research (2020)
The early clinical data is suggestive, and the research community continues to investigate their potential applications
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Lancet Reg Health Am 35:100807
ESR study of the erythrocyte membrane skeletal protein network: influence of the state of aggregation of spectrin on the physical state of membrane proteins, bilayer lipids, and cell surface carbohydrates Biochim Biophys Acta 1985
Notably, eight of the 12 included trials reported beneficial health impacts following raw white garlic consumption, particularly on blood lipid levels, blood pressure (both systolic and diastolic), and antioxidant enzyme activity (e.g., catalase [CAT], superoxide dismutase [SOD], and glutathione peroxidase [GPx])
What the Regulatory Classification Tells Us These medications have historically been treated similarly to Pregnancy Category C drugs: animal studies showed potential risks, and we dont yet have robust human data to know what that means for human pregnancies
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