Higher levels of the stress hormone cortisol can push hair follicles out of the growth phase and into a wave of shedding
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However, youll still feel significantly weakened and tired
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Nat Med 29 , 29932995 (2023)
Such impairments closely parallel the mitochondrial respiratory deficits and elevated oxidative markers reported in cortical and limbic regions of depressed individuals, which would impair energy-dependent neuroplastic processes, intracellular signal transduction cascades, and activity-dependent protein synthesis required for synaptic maintenance, dendritic remodelling, and adaptive circuit function [138, 143]