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and using the lowest effective dose for the shortest duration, while maintaining strict UV protection

This density does not resemble carnitine and is consistent with weak densities observed in substrate-free OCT1 structures 29,30

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Despite the fact that the dimeric macrocycles tightly bind to the ectodomain of human Met and induce various cellular responses in human cells, they did not show any binding activity to that of murine or canine Met (Supplementary Table 3 and Supplementary Fig