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While GLP-1 physiology informs the development of therapeutic agents, the native peptide itself cannot be practically administered for disease management
RS: Involved in manuscript formatting, manuscript review, editing, and approving the manuscript for publication
hold patents US9862678, WO2016075330, EP3218357, and WO2019154795 related to ferrostatin-1 analogs
Heart health risk factors that benefited from the drugs were projected to return to previous levels within 1.4 years, on average
Similarly, a minor increase in plasma TMAO was observed following red meat and processed meat consumption in European multi-center study [72]
Until further evidence is provided, GLP-1 RAs will likely be used preferentially in patients with cardiovascular disease or cardiovascular risk factors
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