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Prolonged overdose of B6 (150-200 mg/day) over weeks can cause severe sensory-nervous-system dysfunction and ataxia.37 With normal usage serious adverse effects are not reported for pyridoxine (vitamin B6), however, diarrhoea, emesis and rosacea-like dermatitis may be observed in some cases (38)

If weight changes occur, they're more plausibly secondary effectsthrough improved recovery, training consistency, or routine adherencerather than guaranteed fat loss

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These effects typically subside within a day

This makes it difficult to absorb dietary B12, even with adequate intake

This dynamic regulation shapes everything from cellular identity to tissue repair and aging trajectories