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The FDA labels for these medications provide comprehensive safety information, with alopecia (hair loss) specifically listed in the Wegovy and Zepbound prescribing information
CJC-1295 (No DAC) is a short-acting GHRH analog
doi: 10.3389/fphar.2026.1754721 Received 26 November 2025 Revised 28 February 2026 Accepted 03 March 2026 Published 19 March 2026 Volume 17 - 2026 Edited by Achuthan Raghavamenon, Amala Cancer Research Centre, India Reviewed by Abdul Rahim Chethikkattuveli Salih, Terasaki Institute for Biomedical Innovation, United States Julio Plaza-Diaz, Childrens Hospital of Eastern Ontario (CHEO), Canada Updates Copyright 2026 Hu, Tian, Yang, Zhang, Zhang, Xu and Lu
Although some GLP-1RAs do not seem to naturally cross the bloodbrain barrier, they may still reach relevant brain areas via circumventricular sites and, possibly, via active transporters 4,5
[2] Lower BMI thresholds may apply for some ethnic groups
GLP1RAs have shown broad cardiometabolic benefits
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