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Adjusting the treatment plan as needed Dose escalation should be dependent of patient side effect profile and gastrointestinal tolerability

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Oral semaglutide must be absorbed through the intestinal tract

However, since semaglutide is a relatively new medication, researchers are still studying how it affects the body over many years, including whether there are any rare side effects that only appear with very long-term use

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The difference often depends on whether specific beneficial bacteria are supported during this transition Tirzepatide and Zepbound Gut Side Effects Tirzepatide is the active ingredient in Mounjaro, prescribed for type 2 diabetes, and Zepbound, prescribed for chronic weight management