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In aged mice, FOXO4-DRI treatment restored fur density, improved renal function, and increased physical activity levels, demonstrating functional rejuvenation through targeted senescent cell clearance

This pattern aligns with B12 pharmacokinetics: serum levels peak 8-12 hours post-injection, tissue saturation occurs over 48-72 hours (Andrs et al., Journal of Blood Medicine , 2018)

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CONCERN #6: LEAKY GUT AND DIGESTIVE DISTRESS Description: Bloating, gas, food sensitivities, and systemic inflammation can often be traced back to a condition known as "leaky gut" or intestinal permeability

Results All of the injured rats that received BPC 157 exhibited consistent clinical improvement, increasingly better motor function of the tail, no autotomy, and resolved spasticity by day 15

Dietary Changes: Winter diets can sometimes be lacking in foods rich in vitamin B12, such as lean meats, fish, and dairy products