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October 9, 2025

The mean SUV was extracted in brain regions: 312, 1922 (the lateral frontal cortex) from the brain Automated Anatomical Atlas 3v1 (AAL3v1) 23 in the MNI space as this region has been observed to show the biggest changes in SUV 24

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Tesofensine has a half-life of approximately 60 hours, meaning it takes 1014 days to reach steady-state plasma levels and the same duration to clear after discontinuation

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