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Glycocalyx structure The glycocalyx is a negatively charged brush-like structure that covers the surface of endothelial cells and extends into the vascular lumen (Fig
doi: 10.3389/fonc.2025.1698320 Received 03 September 2025 Revised 19 November 2025 Accepted 24 November 2025 Published 10 December 2025 Volume 15 - 2025 Edited by Mansoor-Ali Vaali-Mohammed, King Saud University, Saudi Arabia Reviewed by Veenita Khare, University of California, San Diego, United States Rasoul Mirzaei, Hamadan University of Medical Sciences, Iran Erwin Julian, Universitas Indonesia Fakultas Kedokteran, Indonesia Updates Copyright 2025 Yang, Liu, Zou, Liu, Zhou, Tao and Liu
Foods such as red meat, full-fat dairy products, and processed snacks are common culprits
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Discuss dose adjustment with your provider
The compound does not appear to have carcinogenic activity in the models tested, and its interaction with tumor biology, a legitimate concern given that angiogenesis also supports tumor vascularization, has been examined in several studies without evidence of tumor promotion at physiological doses
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