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Clinical chemistry and hematology parameters remain within normal ranges across dose levels and treatment durations

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"Global reconstruction of the human metabolic network based on genomic and bibliomic data"

FIGURE 8 Statements Author contributions YZ, SdB-S, MdB, and SH conducted the experiments and performed the statistical analysis

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For the hepsin / mice, the timing of mortality was such that it occurred prior the onset of liver repair and regeneration processes, thereby confirming the role of hepsin in determining the mechanism of APAP toxicity tolerance during the early phase of drug exposure