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The clinical amylin combination that has actually been studied is CagriSema, which pairs cagrilintide with semaglutide, not tirzepatide
It is a coordination complex: a tripeptide ligand, glycyl-histidyl-lysine, bound to copper in the divalent state through the N-terminal amine, a deprotonated backbone amide nitrogen and the imidazole nitrogen of the histidine side chain
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