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This combination is commonly investigated for its potential roles in gastrointestinal function, immune response, and cellular recovery mechanisms
This system balances redox status by transferring electrons from NADPH to Trx-R, which then reduces disulfide bonds in Trx, allowing it to restore functional thiol groups on various target proteins 60,61
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Its part of the bodys innate defense systemplaying a critical role in maintaining the integrity of the gastrointestinal tract and promoting tissue repair throughout the body
Typically, cytosolic GSTs are hetero- or homo-dimeric proteins and are about 23-30 kDa per monomer
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