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This goes far beyond a generic diet and exercise handout
Stimulation of TGF-1 production in cultured mouse renal tubular cells after complement activation by C3a and C5a binding to C5a receptor and C3a receptor, and stimulation of proximal tubular epithelial cells by MAC leading to increased expression of type IV collagen mediate renal fibrosis resulting in the transition from AKI to CKD [26]
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This approach is determined on a case-by-case basis
It's a direct correlation
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