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For Wegovy (higher-dose semaglutide for weight management), rates were higher, affecting approximately 29.3% of patients across the STEP clinical trials, with most cases occurring during dose escalation phases

10.1023/A:1020339530924

Many experience hot flashes, mood changes, and other symptoms as hormones fluctuate during perimenopause and ultimately decline after menopause

2013;2(6):e000542

The correct framing is: "Weight-loss data suggests Zepbound 10 mg produces outcomes similar to Wegovy 2.4 mg

Their combination in an injectable format marketed for cosmetic outcomes is a relatively recent phenomenon driven by compounding pharmacy channels, not by FDA-approved drug development