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Clinical trials have shown promising results for both medications, but individual responses may vary
Proponents of surgery during the neonatal period often have referenced the scar-less healing associated with fetal development, with the idea being that if surgery is undertaken early in the neonatal period, then fetal-like physiology may still be present and the child will have less scar formation at the surgical site
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For most adults, a safe and effective range is 1,000 to 3,000 mg per day
The SURPASS-2 trial showing tirzepatide achieving significantly greater HbA1c reduction and weight loss than semaglutide in T2DM patients, and the SURMOUNT trials showing up to 22% average body weight reduction in obese patients, have established tirzepatide as the clinical performance leader in the class
