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Taking B12 with or without food makes little difference for standard oral supplements in individuals with normal gastrointestinal function

B12 supplements are typically present in the cyanocobalamin form, which must be converted in the body to active-B12, methylcobalamin and 5-deoxyadenosylcobalamin

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None of it is a prescription, a treatment recommendation, or medical advice

Learn where to self-administer a B12 shot and how to do it painlessly This article was medically reviewed by Shari Forschen, NP, MA and by wikiHow staff writer, Amber Crain