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When medication is appropriate, the discussion should include: The limited evidence for GLP-1 agonists specifically in BED FDA-approved alternatives, including lisdexamfetamine Realistic expectations about outcomes and timeline Potential side effects and monitoring requirements Cost considerations and insurance coverage The importance of combining medication with behavioral interventions Monitoring during treatment should be systematic and multifaceted

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Supplementary Table ( S1 ) shows the funnel plot for publication bias on pulmonary aspiration in GLP-1 agonists and placebo patients

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