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Medicaid coverage for weight loss medications, including GLP-1 receptor agonists like semaglutide (Wegovy) and tirzepatide (Zepbound), varies dramatically from state to sta
However, the clinical significance of this pathway through dietary interventions in humans remains uncertain
Caution is advised in patients with a history of pancreatitis or severe renal impairment
While peptide/aptamer approaches balance synthetic accessibility with potential for rapid renal clearance
Given that both are OAT2 substrates this is possible
Together they increase cardiovascular strain, especially in patients with hypertension or arrhythmia history
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