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Synthesized from the amino acids lysine and methionine, it is primarily stored in muscles, the heart, brain, and kidneys

While herbal treatments interact directly with the gastrointestinal tract and its microbiota, acupuncture primarily works by stimulating specific acupoints on the body surface, which sends afferent neural signals to the central nervous system (CNS) and triggers a series of neuroendocrine responses

NFE2L1-mediated proteasome function protects from ferroptosis

The relation of PPP and G6PD in the detoxification of ROS is determined by the fact that mice deficient in G6PD have higher levels of oxidative damage in the brain