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The observed plasma increase in adenosine could be due to a decrease in adenosine deaminase activity, inhibition of adenosine kinase, or an increase in 5-nucleotidase, all of which can occur in the presence of oxidative stress [7072]
The tripeptide GHK has a strong affinity for copper(II) ions, forming a 1:1 complex that is the biologically active form
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Under low Fe 2+ levels, SifR interacts with free catechol-derived quinones and disengages from the DNA promoter region, resulting in the activation of the SifR regulon
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