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Studies have shown that the peptide demonstrates approximately 40% oral bioavailability in animal models and exhibits rapid metabolism with a serum half-life of approximately 4 minutes, though its metabolic effects persist significantly longer due to downstream cellular activation

People should not take exenatide if they have severe kidney disease, significantly slowed digestion or diabetic ketoacidosis

For those who eat meat and dairy and do not have an underlying issue preventing B12 absorption, this should not be a problem

3 Patients who are resistant to or who cannot tolerate NSAIDs are often prescribed opioids

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