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Individual factors like starting weight, diet, exercise habits, and metabolism all play important roles
| doi:10.1016/j.bbamcr.2016.01.023 Pooyandjoo M, Nouhi M, Shab-Bidar S, Djafarian K, Olyaeemanesh A.: The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials
Managing the Most Common Side Effects Side Effect Timeline Can You Adjust the Dose to Reduce Side Effects
A lot of what were treating is poor dietary habits, he said
If the gap between peak and trough is causing both excess side effects and inadequate efficacy, split dosing addresses both problems simultaneously by flattening the curve in both directions
An early phase 2 trial found the medication may contribute to weight loss of 24.2% of body weight at the 12 mg dose after 48 weeks, with weight loss continuing after the study ended
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