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The 48-week, randomized, double-blind, placebo-controlled study enrolled 469 adults with obesity or overweight with at least one weight-related comorbidity and evaluated multiple dose escalation regimens up to 24 mg administered subcutaneously once weekly
Metabolic checkpoints in activated T cells
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No lethal dose identified at doses up to 20 mg/kg in animal studies No organ toxicity observed across multiple organ systems Negative mutagenicity testing across standard assays No teratogenic effects in pregnancy studies Limited long-term human data beyond 6 weeks Theoretical Considerations The primary theoretical concern relates to BPC-157s angiogenic properties
Standard dosing allows 10 to 20 ml per thigh per session
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