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10.1113/jphysiol.2014.282665 101 SfeirA.de LangeT

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This functional unit strictly depends on the integrity of the gut epithelium, supported by junctional proteins, such as tight junctions (TJs), desmosomes, and adherent junctions, which form a physical barrier and connect adjacent epithelial cells, together with the lamina propria

Gastroenterology 141:150156 Egan AG, Blind E, Dunder K et al (2014) Pancreatic safety of incretin-based drugsFDA and EMA assessment

This approach diversifies risks related to quality, production, or force majeure, resulting in reduced impact compared to a single-supplier strategy