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Your doctor may also monitor you with regular kidney function tests, hearing tests, and urine tests during treatment

The limited human evidence includes: A randomised double-blind placebo-controlled Phase 2 enema trial in ulcerative colitis with 53 participants, published only as a meeting abstract

Mark the vial and discard after two days regardless of appearance

it also found increasing memory impairment as B12 levels dropped even whilst within currently defined acceptable ranges and that B12 interventions are effective once levels are less than 300 pmol/L

The good news is that vitamin B12 is safe, even in large doses

Timeline varies with injury severity, age, and adherence to the protocol your provider sets