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They work by increasing the release of insulin the hormone that controls blood glucose by moving it into cells and suppressing the release of glucagon, which releases glucose from the liver into the blood

Alpha Lipoic Acid is also known as Thioctic acid and is amongst the most powerful naturally occurring antioxidants

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

95% CI 0.89, 0.96), compared with other second- or third-line glucose-lowering medications

Referral to specialist hepatology services may be appropriate for patients with advanced liver disease or diagnostic uncertainty