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Side Effect Profile Sermorelin is generally well tolerated

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As the understanding of resistance mechanisms to TOPI inhibitors emerges (i.e., TOPI mutations and loss of Schlafen 11 (SLFN11), these agents could be deployed to a molecularly selected group of patients as monotherapy or in combinations with PARP inhibitors 38,39

And even if treatment begins 24 hours after overdose, NAC may still improve survival by acting as an antioxidant and supporting liver recovery

& Soares-Mota, M