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[5] [6] Since glutathione, ascorbate and NADPH are present in high concentrations in plant cells it is assumed that the glutathione-ascorbate cycle plays a key role for H 2 O 2 detoxification

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tRNA synthase suppression activates de novo cysteine synthesis to compensate for cystine and glutathione deprivation during ferroptosis

Zoufal et al., 2019), and halogenated derivatives of flavone-based compounds showed MDR-reversing capacity in MRP1 expressing cells (Mavel et al., 2006)