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Semaglutide patents are expiring in several large ex-US markets, enabling cheap generics that could cannibalize Ozempic and Wegovy over time and pressure gross margins further

At present, there are many studies on the purification of Semaglutide, and the purity can reach more than 99%

Eric Topol (05:36): Well, also just to set the foundation here, which you alluded to, there had been so many attempts to come up with a drug that would work, not just of course in diabetes where there are many classes of drugs, but moreover, to treat the condition of obesity

Clinical Trials and Efficacy Data for Oral Semaglutide Early data suggest that oral semaglutide can yield 1015% body weight loss over several months

Inositols help improve insulin sensitivity, but may not be effective for all

It's worth noting that while these effects can be uncomfortable, they're generally part of the body's response to the medication