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Why L-Citrulline Supplementation Outperforms L-Arginine Despite L-arginine's direct role in NO production, L-citrulline offers several advantages as a supplement: Superior Bioavailability - Oral L-arginine undergoes extensive breakdown in the intestines and liver, with approximately 40% degraded during first-pass metabolism

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The evidence summary below is compound-level only

It has been reported that GSTP interacts with JNK, TRAF2, and STAT3 and involves in protecting cells against apoptosis, oxidative stress, and angiotensin II stimulation ( Sepsis, a systemic inflammatory response induced by aggressive infection, is a leading cause of death in intensive care units associated with significant public healthcare problem ( Immune cells recognize not only microorganisms (pathogen-associated molecular patterns

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