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As seen in mice with the deletion of Bdnf in the dentate gyrus, body weight was unaltered in Bdnf flox/flox,Lepr-ires-cre mice ( t (43) = 0.4250, P = 0.6729) (Fig
PMID 8969275
Studied in preclinical metabolic research for its role in the NAD salvage pathway and adipocyte energy metabolism
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Bdnf gene expression in the dentate gyrus is essential for the antidepressant-like effect of leptin We next asked whether Bdnf gene expression in the dentate gyrus is required for leptins depression-related behaviors
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