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[1] Observed mass-spectrometric signals can vary with charge state, adduct formation, isotope distribution, ionization conditions, and data processing

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If a breastfeeding infant experiences an adverse effect related to a maternally ingested drug, healthcare providers are encouraged to report the adverse effect to the FDA

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There is a theoretical case for using both in certain patients, targeting different physiological mechanisms simultaneously, though this approach is under evaluation and not yet standard of care