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Supplementary Figure S2, S3 illustrate the factors influencing the overall risk of bias score (Mcguinness and Higgins, 2021)
However, Wegovy will enjoy a data advantage for the next few years until its competitors manage to catch up with their own outcomes trial readouts, which are not expected until Q4/2027
The problem of discontinuation of the drugs is big, since there are limited data and the likelihood is that the weight will be regained unless there are substantial changes in lifestyle
Researchers from my alma mater University of Connecticut (Storrs) recently published a scientific paper showing that skimping on your post-workout supps is a big mistake
Study 4 was a 68-week trial that enrolled 611 patients with obesity (BMI greater than or equal to 30 kg/m 2 ) or with overweight (BMI 27-29.9 kg/m 2 ) and at least one weight-related comorbid condition such as treated or untreated dyslipidemia or hypertension
DOI Edwards RL, Lyon T, Litwin SE, et al
