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Mice lacking SOD2 die several days after birth, amid massive oxidative stress

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Polizzi FC, Andican G, Cetin E, Civelek S, Yumuk V, Burcak G

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Moreover, in these sporadic cases of severe G6PD deficiency with CGD, PPP flux is markedly diminished to the point of impaired NADPH oxidase activity and absent NETosis (28), and the impaired phagocytic respiratory burst was clinically linked to cases of mycobacterial infection (29)

To this extent, we studied the distribution of MZB precursors (MZP) in adult mice