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Studies show protection against glaucoma with restored intraocular pressure, recovered pupil function, and maintained retinal integrity

Peer review Peer review information Communications Biology thanks Yun Yen and Yilei Zhang for their contribution to the peer review of this work

This macrophage reprogramming is associated with SFN-mediated inhibition of the transcription factor c-Myc, which normally drives M2 polarization, and concurrent activation of the Nrf2 pathway that favors M1-associated gene expression profiles (78)

The ELF GSH levels that occur with the initial adaptive response are roughly 500-600 M (Figure 1A and 4A) while the GSH levels for the maintained adaptive response over repeated CS exposures are only about 250-300 M (Figure 1A)

Reducing inflammation could theoretically benefit various injury types