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However, the renal beneficial effect of SGLT2-i has been definitely reported in recent cardiovascular outcome clinical trials and further confirmed in CREDENCE, DAPA-CKD, EMPA-KIDNEY, which investigated renal outcomes as primary endpoints also in non-diabetic patients with chronic kidney disease (48)
Key takeaways GLP-1s are effective at lowering weight, hemoglobin A1C levels, and cardiovascular risk, but their effects are only sustained if taken continuously
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However, it's essential to be aware of the possible acetyl-L-carnitine side effects and precautions before diving into supplementation
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