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Moreover, clinical studies have begun to explore the therapeutic potential of semaglutide in patients with UC, with preliminary findings suggesting promising outcomes in terms of disease activity reduction, mucosal healing, and improvement in patient-reported outcomes

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BLV exposure (area under the plasma concentration-time curve [AUC]) between ADA+ and ADA patients was similar for 2 mg, AUC ratio (90% CI)=1.22 (1.00-1.51) and for 10 mg, 1.12 (0.96-1.32)

Botfield HF, Uldall MS, Westgate CSJ, Mitchell JL, Hagen SM, Gonzalez AM, Hodson DJ, Jensen RH, Sinclair AJ (2017) A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus

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[1] The most frequently reported adverse effects in clinical trials were gastrointestinal in nature, including nausea (12-22%), diarrhea (12-16%), vomiting (6-10%), and constipation (6-7%), with rates varying by dose