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Further mechanistic investigations have implicated GHK-Cu in the activation of the Nrf2/ARE antioxidant response pathway in cultured cells, where it appears to reduce reactive oxygen species (ROS) burden independently of direct radical scavengingsuggesting an indirect, gene-regulatory mode of action rather than purely stoichiometric antioxidant chemistry

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(Springer International Publishing AG, Cham, Switzerland), 128

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| 2014 | Clinical Nutrition 6Vitamin D: A Micronutrient Regulating Genes Carsten Carlberg | 2019 | Current Pharmaceutical Design 7Comparison of menaquinone-4 and menaquinone-7 bioavailability in healthy women Sato et al

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