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But when you stop tirzepatide, the appetite and digestion support it provides gradually fades, which often means hunger returns, meals feel less filling, and food thoughts or cravings may increase

Presented for research literature review only Christou GA et al

No content here should be interpreted as a treatment recommendation or as a substitute for qualified clinical care

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However, in its initial draft guidance, published on 27 June 2023, the committee concluded there were uncertainties in the clinical evidence and issues with the companys economic model