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By activating GIP and GLP-1 receptors, tirzepatide enhances insulin secretion when blood glucose levels are elevated, suppresses glucagon release, slows gastric emptying, and reduces appetite through effects on brain centers that control hunger
Low electrolyte levels and poor hydration may cause lightheadedness, dizziness, or weakness
Still, some drugs, like haloperidol, which is used to treat mental disorders like schizophrenia, have been found to cause damage to the stomach lining [6]
That explains why lipid shifts commonly follow in the months after starting therapy and why clinicians repeat lipid testing to capture meaningful change
As some researchers are looking at how they can deliver GLP-1s in vivo, others are looking beyond GLP-1 peptides altogether
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